You must be spirit

"God is Spirit, and those who worship Him must worship in spirit and truth.” John 4.24

Because of His holy nature, God rejects the worship of those who DO NOT have the same divine nature.
How could those who are born of the blood, the will of the flesh or the will of man express sublime and profound praises to Someone who is Spirit? Is it possible for the flesh to worship in spirit?
To worship in spirit, you must be born of the Spirit. You must have His DNA, His nature, in other words, you MUST BE SPIRIT!

You ask amiss

"...You ask and do not receive, because you ask amiss, that you may spend it on your pleasures." James 4.3

Because of their fleshly nature, the children of the world ask and do not receive, since they ask to satisfy the flesh. But the children of God, when ask according to His will, receive.

GOD'S JUSTICE

"For the eyes of the Lord are on the righteous, and His ears are open to their prayers, but the face of the Lord is against those who do evil."    1 Peter 3.12

Because of His righteous nature, God hates unrighteousness. He abominates everything that is evil or sinful.
However, suffering is not His form of punishment. Instead, sinners reap the fruits of their sins. And He does not interfere with this. 
But, for those who are righteous, His eyes are on them and His ears are open to their prayers.

Children of God

"The Spirit of God has made me, and the breath of the Almighty gives me life." Job 33:4

Adam and Eve were creatures of God. Through them, humanity developed without divine intervention. Following through the natural Law of nature fixed by God. With the birth of the Lord Jesus, through the Holy Spirit, a new generation of children of God began.  The Holy Spirit has been at work with everyone who unconditionally gives his life  to God.

Hated

"I have given them Your word; and the world has hated them because they are not of the world, just as I am not of the world." John 17:14

The Word of God transformed us into new creatures, fulfilled in happiness and goodness. For this reason, those who are still in their old nature, who don't know the One responsible for our changes, hate us.